| 학회 |
한국고분자학회 |
| 학술대회 |
2015년 가을 (10/06 ~ 10/08, 대구컨벤션센터(EXCO)) |
| 권호 |
40권 2호 |
| 발표분야 |
고분자합성 |
| 제목 |
Novel Practical Method for 1-Hydroxypyrene Determination in Urine by Using Molecularly Imprinted TiO2 Gel |
| 초록 |
A novel method for detecting 1-hydroxypyrene (1-OHP) in human urine by using molecularly imprinted TiO2 gel was developed. This method can be practically applied on patients in a hospital to estimate the degree of exposure to polycyclic aromatic hydrocarbons. We first attempted 1-OHP molecular imprinting to deposit TiO2 gel thin films on quartz plates. After 1-OHP template removal, the 1-OHP-imprinted films showed better recognition and higher selectivity toward 1-OHP than toward other similar materials. The results obtained were applied to bead materials to enlarge their surface area; such beads could have practical application in a hospital. 1-OHP-imprinted beads were used to extract and collect 1-OHP from a patient’s urine by an easy and simple method, and the 1-OHP amount was detected using HPLC. This method is very accurate, as well as cheaper and faster than the enzyme-based method that was previously used in the hospital. |
| 저자 |
신재섭, 김민희, 김승기, 양도현
|
| 소속 |
충북대 |
| 키워드 |
1-hydroxypyrene; urine; molecular imprinting; TiO2 gel
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| E-Mail |
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