| 학회 |
한국공업화학회 |
| 학술대회 |
2020년 가을 (10/28 ~ 10/30, 광주 김대중컨벤션센터(Kimdaejung Convention Center)) |
| 권호 |
24권 1호 |
| 발표분야 |
포스터-생물공학 |
| 제목 |
3D microwell culture for regulating self-renewal and differentiation of neural stem cells |
| 초록 |
Neural stem cells may provide effective therapeutics for treating neurodegenerative diseases and traumatic brain injury. Therefore, engineering 3D culture system can directly affects neural stem cell behaviors. Conventional 3D culture platforms have several limitation such as labor intensiveness, non-uniform size contorl and no accessibility of additional fresh growh medium. Microwell, a 3D cell culture system overcome these limitations, easy to control, high throughput, uniform size control and co-culture available in this system. Size-controlled human fetal neural stem cells cultured on microwell exhibit enhanced self-renewal properties and differentiation abilities. Our study suggestes the 3D culture platform, microwell, may used for various research fields like clinical application and basic neurogenesis. This work was supported by a grant (2017M3C7A1047659) from the National Research Foundation of Korea (NRF) funded by the Ministry of Science and ICT (MSIT), Republic of Korea. |
| 저자 |
이종승1, 양기석1, 한세운2, 장경언1, 정은지1, 정석2, 조승우1
|
| 소속 |
1연세대, 2고려대 |
| 키워드 |
Microwell; Human neural stem cell; Neurogenesis; Vasculature
|
| E-Mail |
|
