| 학회 |
한국공업화학회 |
| 학술대회 |
2019년 봄 (05/01 ~ 05/03, 부산 벡스코(BEXCO)) |
| 권호 |
23권 1호 |
| 발표분야 |
생체재료_포스터 |
| 제목 |
Simultaneous delivery of antigen and immune response modifier via dissolving microneedle array for enhanced cancer vaccine |
| 초록 |
Microneedles (MNs) is a non-invasive way to deliver painlessly the therapeutic contents through the stratum corneum. Among MNs, dissolving MNs can be constructed with different materials that dissolve quickly after its action on the skin. We focused on use of immune activators such antigen and immune response modifier for enhanced immune response in immunotherapy. We developed a pluronic-based microneedle which contains micro micelles loading immune adjuvants and cancer antigen vaccine. As a model therapeutic cancer vaccine, ovalbumin (OVA) and resiquimod (R848) used as antigen and imidazoquinoline-based compounds. |
| 저자 |
김동민, 정지훈, 정재백, 임수연, 김이슬, 김다훤
|
| 소속 |
성균관대 |
| 키워드 |
Microneedle cancer vaccine |
| E-Mail |
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