화학공학소재연구정보센터
학회 한국재료학회
학술대회 2008년 가을 (11/07 ~ 11/07, 차세대융합기술연구원)
권호 14권 2호
발표분야 나노생체재료
제목 New Design of Coronary Bypass Artery with PCL Layer and PLGA/Chitosan Mat Using Electrospinning
초록 A coronary graft fabricated from PLGA poly (lactic-co-glycolic acid) and chitosan electrospuns deposited on poly caprolactone (PCL) tube. PCL tube showed high stable shape, mechanical response of a compliant dynamic flow conditions fabricated by solvent evaporation. With high surface to volume ratio and porosity of poly (lactic-co-glycolic acid) (PLGA)/Chitosan electrospun nanofibers were thought to mimic natural extra cellular matrix (ECM) and thus promoted fibroblast adhesion, migration and proliferation. Mechanical properties, morphology, inner/outer diameter and thickness of tubes were characterized.
저자 Thi-Hiep Nguyen, In-Seon Byun, Young-Ki Min, Ho-Yeon Song, Byong-Taek Lee
소속 Soonchunhyang Univ.
키워드 PLGA; PCL; Chitosan; Electro spinning; Mechanical
E-Mail