| 초록 |
We present a one-pot route for preparation of monodisperse poly(N-isopropylacrylamide) (PNIPAM) microcapsules using microfluidic chip. Emulsions of NIPAm phase were generated by immiscible continuous phase containing photoinitiators. Under UV exposure, free radicals are diffused into the interface between the continuous phase and the NIPAm emulsion which induced polymerization of NIPAM monomers. The PNIPAM microcapsules were hollow microcapsules with a thin shell membrane, high monodispersity, and fast response to temperature. In addition, the size of microcapsules produced could be controlled by the flow rate of the continuous phase or aqueous phase and different concentrations of surfactant to chan interfacial tension between continuous phase and aqueous phase. Furthermore, this microfluidic approach enables the preparation of monodisperse microcapsules having the capability to encapsulate various materials such as proteins and nanoparticles. |
