| 학회 |
한국고분자학회 |
| 학술대회 |
2012년 봄 (04/12 ~ 04/13, 대전컨벤션센터) |
| 권호 |
37권 1호 |
| 발표분야 |
의료용고분자 부문위원회 |
| 제목 |
Effect of Physical/Biological Stimulations on Peripheral Nerve Regeneration through Nerve Guide Conduit with Selective Permeability |
| 초록 |
The sufficient functional recovery of damaged peripheral nerves has been considered as one of the clinical challenges. Artificial nerve guide conduits (NGCs) to bridge the gap between severed nerve stumps are widely accepted as an useful alternative that creates a favorable environment for nerve regeneration. In this study, we applied physical (ultrasound) and biological (nerve growth factor, NGF) stimulations at the asymmetrically porous polycaprolactone (PCL)/Pluronic F127 nerve guide conduit (NGC) for enhanced nerve regeneration. From the results, it was recognized that the asymmetrically porous NGC group with both physical and biological stimulations had more rapid nerve regeneration behavior than the NGC groups with single stimulation or without stimulation. (This work was supported by the National Research Foundation of Korea (Grant No. NRF-2011-0000244)). |
| 저자 |
김진래1, 오세행1, 권구범2, 남궁욱2, 송규상3, 전병화3, 이진호1
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| 소속 |
1한남대, 2대전대, 3충남대 |
| 키워드 |
Physical / Biological Stimulations; Nerve Guide Conduit
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| E-Mail |
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