| 학회 |
한국공업화학회 |
| 학술대회 |
2016년 봄 (05/02 ~ 05/04, 여수 엑스포 컨벤션) |
| 권호 |
20권 1호 |
| 발표분야 |
(무기재료)이차원 나노소재의 광범위한 확장성 및 잠재적 가치 |
| 제목 |
Biosensors based on Graphene Oxide for Diagnostics and Drug Discovery |
| 초록 |
In this talk, I will introduce recent studies which harness graphene derivatives for developing bioanalytical platforms to quantitatively analyze various enzyme activities and biomarkers including helicase and microRNA. The systems rely on attractive interaction between graphene oxide and nucleic acids and fluorescence quenching by graphene oxide. Quantitative microRNA sensing was successfully demonstrated in living cells. Recently, we employed one of the graphene-based bioassay systems to anti-viral drug screening and identified potent hit compounds to treat hepatitis C. This study shows that a new nanobio-technology can be routinely implemented in drug discovery with high-throughput capability, providing many advantages over conventional methods. |
| 저자 |
민달희 |
| 소속 |
서울대 |
| 키워드 |
Graphene Oxide; Biosensors; Drug screening
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| E-Mail |
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