| 학회 |
한국공업화학회 |
| 학술대회 |
2016년 봄 (05/02 ~ 05/04, 여수 엑스포 컨벤션) |
| 권호 |
20권 1호 |
| 발표분야 |
(생체재료)메디컬용 나노입자 |
| 제목 |
Near Infrared-Assisted Transdermal Hydrogel Formation |
| 초록 |
Common light sources (i.e., ultraviolet and visible light) strongly interact with biological systems and are therefore inappropriate for in vivo applications, such as transdermal polymerization. Using near infrared (NIR) light that minimally interacts with living tissues, we investigate NIR light-assisted photothermal polymerization (NAPP) of diacrylated polyethylene glycol (PEGDA), in which interactions between NIR light and gold nanorods activate a thermal initiator for polymerization of PEGDA. Gelation parameters are investigated to minimize the use of initiator and temperature increases during NAPP. Cell viability is as high as 80% after NAPP-based encapsulation. Incorporation of PEG modified with a cell-adhesive peptide moiety into the gel system further enables prolongation of cell viability during incubation up to 7 days. NAPP results in successful transdermal gelation and good viability of the transplanted cells |
| 저자 |
이재영1, 이황재2, 정솔찬2
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| 소속 |
1광주과학기술원, 2광주과학기술원 신소재공학부 |
| 키워드 |
Near infrared; gold nanorods; hydrogels; injectable; phototherma;
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| E-Mail |
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