| 학회 |
한국공업화학회 |
| 학술대회 |
2021년 가을 (11/03 ~ 11/05, 대구 엑스코(EXCO)) |
| 권호 |
25권 2호 |
| 발표분야 |
포스터-생물공학 |
| 제목 |
High Electron Mobility Transistor(HEMT) Based Cortisol Sensing Using 2 nm Gold Nanoparticles as Aptamer Binding Beacon |
| 초록 |
Recently, monitoring of cortisol concentration can be an important indicator to evaluate the overall physiological status or mental disease like post trauma syndrome disorder(PTSD). In this study, cortisol is sensed using a AlGaN/GaN High Electron Mobility Transistor (HEMT) and three different aptamer probes that selectively binds to cortisol were examined. For the effective indicator of aptamer probing ability, 2 nm gold (Au) nanoparticles (NPs) were synthesized and utilized as a beacon of the aptamer binding toward cortisol. The sensing mechanism is based on the change in resistance with the target sample binding to the HEMT sensing surface layer. In addition, low limit of detection (LOD) was attained by increasing sensing sensitivity using 2 nm Au NPs. |
| 저자 |
오승주, 김초롱, 허혜연, 양종민, 신성철, 김길환, 이현호, Dhanashri Vitthal Desai
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| 소속 |
명지대 |
| 키워드 |
HEMT; cortisol; aptamer; gold nanoparticles
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| E-Mail |
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