| 학회 |
한국화학공학회 |
| 학술대회 |
2008년 가을 (10/23 ~ 10/24, 부산 BEXCO) |
| 권호 |
14권 2호, p.2745 |
| 발표분야 |
생물화공 |
| 제목 |
Deletion of oadGAB operon in Mannheimia succiniciproducens |
| 초록 |
Oxaloacetate decarboxylase complex, encoded by oadGAB operon in M. succiniciproducens, is predicted to convert oxaloacetate into pyruvate, while competing with malate dehydrogenase leading to succinic acid production. As a verification of the homology analysis, oadGAB operon of M. succiniciproducens was deleted using a markerless gene deletion method. The fermentation of oadGAB deletion mutant verified that oxaloacetate decarboxylase did not affect the succinic acid production of wild type M. succiniciproducens. |
| 저자 |
김지만1, 이상엽2
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| 소속 |
1Metabolic and Biomolecular Engineering National Research Laboratory, 2Department of Chemical & Biomolecular Engineering and BioProcess Engineering Research Center |
| 키워드 |
Mannheimia succiniciproducens; oxaloacetate decarboxylase; succinic acid; fermentation
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| E-Mail |
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| 원문파일 |
초록 보기 |
