| 학회 |
한국화학공학회 |
| 학술대회 |
2019년 가을 (10/23 ~ 10/25, 대전컨벤션센터) |
| 권호 |
25권 2호, p.1773 |
| 발표분야 |
이동현상 (Transport Phenomena) |
| 제목 |
Synthesis of Multi-Stimuli Responsive Drug Carrier for Selective Drug Release to Tumor Microenvironment |
| 초록 |
Multi-stimuli responsive drug carriers have been actively researched for controlled drug release in complex tumor microenvironments. In addition to the stimuli responsive drug release, combinatorial chemotherapy is essential to increase therapeutic effects. However, previous studies have shown limitation in the synthesis of multi-compartmental drug carriers that can encapsulate multiple drugs and release each drug in a controlled manner. Here, we report multi-stimuli responsive drug carriers containing pH- and redox-sensitive multi-compartments. The drug carriers were created by stop flow lithography that can be used to synthesize multi-compartmental particles. The carriers exhibited independent drug release upon exposure to the corresponding stimulus. |
| 저자 |
문석준1, 김현웅1, 최대건2, 이현지1, 봉기완1
|
| 소속 |
1고려대, 2인천대 |
| 키워드 |
이동현상 |
| E-Mail |
|
| 원문파일 |
초록 보기 |
