초록 |
Skin, the largest organ in human body, impedes the flux of toxins into the body and minimizes water loss, providing an excellent barrier property to the penetration of foreign materials. This is due to the presence of the stratum corneum that has a unique hierarchical structure mainly consisting of corneocytes and lipid-rich intercellular matrix, which leads to a variety of biological, chemical, and mechanical complex features and functions. From understanding on the skin, this talk introduces flexible and straightforward methods for development of a variety of cosmetic materials that are fabricated by assembly of amphiphiles. We deal with recent advances in fabricating complex lipid particles, polymeric nanocapsules, and nanoemulsions. These materials have great potentials for developing a variety of cosmetic formulations that can not only encapsulate active ingredients, but also show responsiveness for environmental factors, such as pH, salts, and heat. |