| 학회 |
한국고분자학회 |
| 학술대회 |
2013년 봄 (04/11 ~ 04/12, 대전컨벤션센터) |
| 권호 |
38권 1호 |
| 발표분야 |
고분자합성 |
| 제목 |
Preparation and Release Property of Alginate Microsphere Immobilizing hydroxyethyl acrylate-coumarin acrylate-ethylhexyl acrylate copolymer |
| 초록 |
Alginate microsphere was used to prepare W/O emulsion method, then adding calcium chloride as a crosslinker to form the gel, filtrating and washing, we obtain th microsphere. Alginate microspheres containing hydroxyethyl acrylate-coumarin acrylate-ethylhexyl acrylate(HEA-AC-EHA) copolymer were prepared. HEA-AC-EHA is usually used as tempreature-senstive material. The lower critical solution temperature (LCST) of the polymer was found on a UV/Vis spectrometer. LCST of copolymers is about 27oC. The copolymers can be used as release controlled valve in drug delivery vehicles like alginate microsphere. The temperature-dependent release property of the microsphere was observed using FITC-dextran (Fluorescein isothiocyanate-dextran) as a dye. Around 60% was released in 8h according to our study. |
| 저자 |
조창현, 김진철
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| 소속 |
강원대 |
| 키워드 |
Temperature-senstive; Alginate; Microsphere; hydroxyethyl acrylate-co-coumarin acrylate-co-ethylhexyl acrylate
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| E-Mail |
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