화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2002년 봄 (04/12 ~ 04/13, 서울대학교)
권호 27권 1호, p.283
발표분야 의료용 고분자 부문위원회
제목 The Preparation of Chitin Gel using α,β,γ-Chitin as a Sustained Release Matrices Forms
초록 α,β,γ-chitin were isolated from natural resources by treatment with NaOH solution and for deprotenization, and then by treatment with dilute HCl solution for demineralization. The chitin gel matrices were prepared using α,β,γ-chitin for application of drug delivery systems.
In this study, α,β,γ-chitin were isolated from crab shell, squid pen and beetles of cuticle, respectively, and physicochemical properties were investigated using fourier transform infrared spectrometer, X-ray diffractometer, and differential scanning calorimeter. And then the chitin gel matrices were prepared using α,β,γ-chitin and dissolution characteristics of drug from chitin gel matrices were investigated.
The dissolution profiles of α,β,γ-chitin gel matrices were determined by means of available compendium. Dissolution efficiency of these gel matrices were observed at 37± 0.5℃.
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