| 학회 |
한국고분자학회 |
| 학술대회 |
2008년 가을 (10/09 ~ 10/10, 일산킨텍스) |
| 권호 |
33권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Microfluidicapproach for generation of monodisperse Tadpole-like alginate particles |
| 초록 |
The simple microfluidic approach for the generation of monodisperse Tadpole-like alginate particles is presented. Emulsions of alginate solution are uniformly pinched off at T-shaped junction as immiscible phase. Alginate emulsions generated in microfluidic device were transferred into reaction bath dissolving CaCl2 as cross-liking agent. Emulsions flowing along the microchannel were directly solidified when they are contacting with CaCl2. Spherical emulsions were transformed into Tadpole-like algiante gel structures according to their change of reaction rate which was also controlled by concentration of cross-liking agent and alginate solution. Furthermore, microfluidic method could manipulate size of produced alginate particles with the control of flow rate. Finally, FITC-BSA was encapsulated in alginate particles as model of drugs. |
| 저자 |
최창형, 정재훈, 이창수
|
| 소속 |
충남대 |
| 키워드 |
Tadpole-like; Alginate; Microfluidics
|
| E-Mail |
|
