| 초록 |
Inspired by melanogenesis found in biological systems, we have developed an enzyme cascade system for artificially forming melanin-like species (MLS). Specifically, the combination of glucose oxidase and horseradish peroxidase enables the polymerization of various ortho-diphenols, including protocatechuic aldehyde and pyrocatechol. The developed system has been advantageously applied to the cytocompatible single-cell nanoencapsulation (SCNE) of Saccharomyces cerevisiae. Regarding the potential utility of MLS in diversified sectors, the enzymatic system developed in this work will provide an advanced tool for manipulating MLS and fabricating MLS-based nanoarchitectures. |
