| 초록 |
Different non-covalent approach such as bulk polymerization and in-situ copolymerization strategies for preparing selective molecularly imprinted polymers were investigated and compared by using methacryclic acid and acrylamide as monomers, ethylene glycol dimethacrylate/ trimethylolpropane trimethacrylate as cross-linkers, and acetonitrile, methanol and water as porogenic solvent. Binding capability, morphological characteristics, and chromatographic properties of the molecularly imprinted polymers were investigated and the results revealed that the obtained polymers have high affinity and selectivity for template molecule and its analogues in both nonpolar and aqueous system. Effects of imprinting recognition were also discussed and the results show that electrostatic action and hydrophobic interactions between the template molecule and the imprinted polymers play an important role in the recognition process. The synthesized molecularly imprinted polymers were successfully applied as chromatographic stationary phase for the enrichment and separation potentials analytes in biological and environmental samples. |
