| 초록 |
Fish are the most widely used non-mammalian vertebrates in risk assessment and regulation. Several fish species are recommended for standard testing of chemicals or environmental samples. Among them, zebrafish has special characteristics, which expedite its use as a model organism. The vertebrate zebrafish (Daniorerio) is a small tropical freshwater fish that has emerged as a highly advantageous vertebrate model organism because of its small size, large clutches, transparent, low cost, and the development of the zebrafish is very similar to the embryogenesis in higher vertebrates, including humans. Traditionally, zebrafish has been used in the fields of molecular genetics and developmental biology. This study evaluated the biological activities, anti-inflammatory and anti-melagenicactivities of natural productsusing zebrafish and embryo as an alternative in vivo model. |
