| 학회 | 한국공업화학회 |
| 학술대회 | 2018년 가을 (10/31 ~ 11/02, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 | 22권 2호 |
| 발표분야 | 생물공학_포스터 |
| 제목 | Adsorption Kinetics, Mechanism, Isotherm, and Thermodynamic Analysis of Paclitaxel from Taxus chinensis onto Sylopute |
| 초록 | Abstract Batch experiment studies were carried out on the adsorption of paclitaxel from Taxus chinensis onto Sylopute. The experimental data were fitted to the Langmuir, Freundlich, Temkin and Dubinin-Radushkevich isotherm models. Comparison of results revealed that the Langmuir isotherm model could account for the adsorption isotherm data with the highest accuracy among the four isotherm models considered. From the analysis of adsorption isotherms, it was found that adsorption capacity increased with increasing temperature and the adsorption of paclitaxel onto Sylopute was favorable. The obtained kinetics data for paclitaxel adsorption onto Sylopute agreed well with the pseudo-second-order model. Thermodynamic parameters, such as standard enthalpy (△H°), standard entropy (△S°) and standard Gibbs free energy (△G°) change, were investigated. The results indicated that the process of paclitaxel adsorption onto Sylopute was endothermic, irreversible and nonspontaneous. |
| 저자 | 강회종, 김진현 |
| 소속 | 공주대 |
| 키워드 | Paclitaxel; Sylopute; Adsorption Isotherm; Kinetics; Thermodynamics |
