학회 |
한국화학공학회 |
학술대회 |
2015년 가을 (10/21 ~ 10/23, 일산 KINTEX) |
권호 |
21권 2호, p.1783 |
발표분야 |
생물화공 |
제목 |
L-DOPA synthesis using electrochemically pretreated graphite/nafion modified GCE |
초록 |
Levodopa or L-3,4-dihydroxyphenylalanine (L-DOPA) is the precursor of the neurotransmitter dopamine. L-DOPA is a famous treatment for Parkinson’s disease symptoms. In this study, electroenzymatic synthesis of L-DOPA was performed in a three electrode cell, comprising a Ag/AgCl reference electrode, a platinum wire auxiliary electrode, and a glassy carbon working electrode. We conducted some immobilization modified working electrode using graphite to improve reusability of enzyme. Electrochemically activated graphite/nafion composite was prepared by using a simple electrochemical method. Optimizations of experimental variables, such as the pH, temperature, operational and storage stability experiments were investigated. Kinetic parameter of enzyme and electrode was also studied. |
저자 |
박돈희1, Jae-Hee Park2, Seok-Hwan Park1, Hyoung-Min Lee3, Siti Fauziyah Rahman1
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소속 |
1Interdisciplinary Program of Graduate School for Bioenergy and Biomaterials, 2Chonnam National Univ. / Department of Biotechnology & Bioengineering, 3Chonnam National Univ. |
키워드 |
Graphite; L-DOPA; Electrochemical pretreatment; tyrosinase enzyme
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E-Mail |
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원문파일 |
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