| 학회 |
한국고분자학회 |
| 학술대회 |
2010년 봄 (04/08 ~ 04/09, 대전컨벤션센터) |
| 권호 |
35권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Articular Cartilage Regeneration Using PLGA Scaffold Penetrated Hyaluronic Acid Solution, in vivo |
| 초록 |
Adult articular cartilage tissue has difficult self-renewal. Therefore, tissue engineering approach are decided by the clinical trial to regenerate repair. PLGA and hyaluronic acid have biodegradability and biocompatibility. The HA/PLGA scaffold were prepared by simple method that PLGA scaffolds manufactured by solvent casting/salt leaching method soaked in hyaluronic acid solution. The chondrobytes were seeded on the HA-PLGA scaffolds Through SEM was confirmed that HA solution was put into the pores of PLGA scaffold. Biological assay for collagen and sGAG, and PCR were performed. The HA/PLGA were cell viability higher then only PLGA scaffolds. This reserch was supported by SCRC(SC4110) and WCU(R31-20029) |
| 저자 |
유현, 서한솔, 김혜린, 엄신, 이동원, 강길선
|
| 소속 |
전북대 |
| 키워드 |
Chondrocyte; PLGA; Hyaluronic acid(HA); Scaffold
|
| E-Mail |
|
