| 학회 |
한국고분자학회 |
| 학술대회 |
2021년 봄 (04/07 ~ 04/09, 대전컨벤션센터) |
| 권호 |
46권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 Ⅰ |
| 제목 |
Injectable Hybrid Hydrogels with Versatile Properties for Various Biomedical Applications |
| 초록 |
Gelatin hydrogels have been extensively used in pharmaceutical and medical applications due to biocompatibility and biodegradability. However, it is difficult to control the properties of natural polymer-based hydrogel without any modification. To overcome this, natural/synthetic hybrid hydrogels incorporating PEG into gelatin hydrogels could control their properties with biocompatibility. In this study, we prepared gelatin/PEG hybrid hydrogels depending on the lengths and contents of PEG, formed by enzyme-mediated crosslinking. The physicochemical of hydrogels were independently adjusted by PEG parameters with cyto-compatibility. Furthermore, the formulation with the highest physicochemical properties showed effective hemostasis and wound healing in vivo. In conclusion, the gelatin/PEG hybrid hydrogels with tunable physicochemical properties could be expected to be a promising biomaterial for various applications. Acknowledgement: NRF-2019R1A6A1A11051471 & 202012A01 |
| 저자 |
황진영, 이시민, Le Thi Phuong, 박기동
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| 소속 |
아주대 |
| 키워드 |
Hybrid; Hydrogel; Physicochemical property; Biomaterial
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| E-Mail |
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