| 학회 |
한국고분자학회 |
| 학술대회 |
2003년 가을 (10/10 ~ 10/11, 부경대학교) |
| 권호 |
28권 2호, p.386 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Cell Adhesion and Growth Behavior on Electrospun Nanofibrous Sheets |
| 초록 |
The architecture of an engineered tissue substitute plays an important role in modulating tissue growth. A large number of research groups have recently studied the interaction of biomedical materials with cultured tissue cells because cell-compatible materials are thought to be very important in many tissue engineering applications. Electrospinning is a fabrication process that can produce nonwoven, highly porous nanometer-scale fiber-based matrices using an electrostatically driven jet of polymer solution or melt. The method represents an attractive approach for polymeric biomaterial processing which provides the morphology similar to extracellular matrix that may retain mechanical strength, flexibility, and high porosity. In this study, we fabricated polycarprolactone (PCL) nonwoven nanofibrous sheets and coated them with cell-adhesive protein, collagen. The tissue cell adhesion and growth behavior of the nanofibrous sheets with/without the coating of collagen as well as control nonporous PCL sheets was compared by in vitro cell culture using fibroblast and muscle-derived stem cell.
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| 저자 |
조상호1, 오세행1, 이지열2, 이근형3, 김학용3, 이진호1
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| 소속 |
1한남대, 2가톨릭대, 3전북대 |
| 키워드 |
electrospinning; cell adhesion; cell growth
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| E-Mail |
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