| 초록 |
Polymersome-based nanoreactors encapsulate a variety of catalysts including nanoparticles and enzymes within the water-filled inner compartment. A key requirement of the bilayer membranes of the nanoreactor is a tunable porosity that allow the transportation of reagents and products while retaining the catalysts within the compartment for chemical transformation for a long period. Here, we report the stimuli-responsive route for controlling the permeability of the polymer bilayers. We self-assembled the binary blends of PEG-b-PS and PEG-b-PABB(poly(acrylbenzylborate)) into polymersomes in water. On introduction of H2O2, the borate units are oxidized, resulting in the formation of PEG-b-PAA(poly(acrylic acid)). By controlling the composition of two BCPs, polymersomes of the binary blends exhibited size-selective permeability without losing the structural integrity. This size-selectivity arises from the phase-separation between the inert PS and the stimuli-responsive PABB blocks. |
