초록 |
Asymmetric PSi-based optical biosensor was developed to specify the biomolecules. Asymmetric PSi was generated by an electrochemical etching of silicon wafer using an asymmetric electrode configuration in aqueous ethanolic HF solution. The sensor system studied consisted of monolayer PSi modified with biotin. When the biotin-derivatized asymmetric PSi was exposed to avidin in PBS buffer solution, molecular binding caused an increase of its effective optical thickness. The changes of effective optical thickness at different positions of asymmetric PSi were measured to specify the biomolecules. |