| 학회 | 한국고분자학회 |
| 학술대회 | 2002년 봄 (04/12 ~ 04/13, 서울대학교) |
| 권호 | 27권 1호, p.289 |
| 발표분야 | 의료용 고분자 부문위원회 |
| 제목 | Demineralized Bone Particle Impregnated PLGA Scaffoldsand Osteogenic Differentiation of BMSCs for Tissue Engineered Bone in vitro Study |
| 초록 | Poly(L-lactide-co-glycolide) (PLGA 50:50, Mw; 110000 g/mole) scaffolds have been utilized for the regeneration of various tissues and organs including bone formation. In this study, bone marrow stromal cells (BMSCs) were demonstrated the mechanism of osteogenic differentiation onto demineralized bone particle impregnated PLGA (DBP/PLGA) scaffolds. We studied the role of BMSCs reconstituted DBP/PLGA scaffolds in vitro during 3, 4, and 6 weeks. Differential cell morphology was observed by H&E staining and scanning electron microscopy (SEM). Specific characteristics of osteoblasts were used to assess osteogenic differentiation with von Kossa staining and alkaline phosphate activity. Acknowledgement: This study was supported by MOICE. |
| 저자 | 김인영1, 장지욱2, 이상진*3, 강길선**4, 이 봉5, 이일우***6, 성진형****, 이해방***** |
| 소속 | 1부경대, 2*한양대, 3**전북대, 4***가톨릭의과대, 5****가톨릭의과대, 6*****한국화학(연) |
| 키워드 | |
