| 학회 |
한국고분자학회 |
| 학술대회 |
2012년 가을 (10/11 ~ 10/12, 창원컨벤션센터) |
| 권호 |
37권 2호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Synthesis and biocompatibility properties of polyester containing various diacid based on isosorbide. |
| 초록 |
Biocompatible polyesters were prepared from isosorbide and various aliphatic diacids via a simple non-solvent polycondensation with a low toxicity catalyst. The successful synthesis of the polyesters was confirmed by gel permeation chromatography,1H-nuclear magnetic resonance and Fourier transform-infrared spectroscopies and differential scanning calorimetry. The degradation tests were performed at 37oC in phosphate buffer solution(approx.pH7.3). The in vitro cytocompatibility test results following culture of osteoblasts on the polymer surface showed that relative cell number on poly(isosorbide sebacate) and poly(isosorbide adipate) films after 5 days of cultured on polymer films was similar to those on the tissue culture plastic. These polymers offer significant promise due to the simplicity of the synthesis and the controlled degradation. |
| 저자 |
박형석, 공명선, Jonathan C Knowles
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| 소속 |
단국대 |
| 키워드 |
polyester; degradable; isosorbide; biocompatible; polycondensation.
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| E-Mail |
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