| 초록 |
Plastic production has increased around the world and processing used petroleum-based plastics generates greenhouse gases such as CO2. Therefore we need to substitutes for petroleum-based plastics and one of them is bioplastics. Among the various bioplastics, polyhydroxybutyrate(PHB) is promising because it is similar to polyproplyene(PP), the main component of conventional plastics. A novel PHB-producing cyanobacterial strain was developed by harnessing fast-growing cyanobacteria Synechococcus elongatus UTEX 2973 with introduction of heterologous phaCAB genes. Under photoautotrophic condition, the engineered strain produced 420 mg L-1 with the highest specific productivity of 75.2 mg L-1 d-1. When compared with a native PHB producer Synechocystis PCC 6803 under nitrogen deprivation, the engineered strain exhibited 2.4-fold higher PHB productivity. This study can provide a promising solution to address petroleum-based plastic waste and contribute to CO2 mitigation. |
