| 초록 |
Lanthanide-doped upconversion nanoparticles (UCNPs) have emerged as an important class of nanomaterials due to thier high photostability, long luminescence lifetime, low autofluorescence backgroud, and deep tissue penetration depth. However, since the Yb3+-sensitized UCNPs respond to the light of 980 nm wavelength, which is well absorbed by water molecules, they have some limitations of overheating or penetration depth in tissue. In this study, Nd3+-sensitized UCNPs with a core-shell structure were synthesized by hydrothermal method. The surface modification of UCNPs was conducted for biodetection and photodynamic therapy (PDT) application. In addition, the photoluminescence properties and PDT effects of the surface-modified UCNPs were investigated. |
