| 학회 | 한국화학공학회 |
| 학술대회 | 2010년 봄 (04/22 ~ 04/23, 대구 EXCO) |
| 권호 | 16권 1호, p.382 |
| 발표분야 | 생물화공 |
| 제목 | Overexpression of transcription factor SPT3 in engineered Saccharomyces cerevisiae using glycerol for improving ethanol production |
| 초록 | Ethanol plays an important role in substituting more and more limited petrol as the high value renewable power fuel for industrial application. In our previous article, we successfully established the conversion of glycerol to ethanol by engineered Saccharomyces cerevisiae [1]. However the ethanol yield is still relatively low. Hence, enhancing ethanol and osmotic tolerance in ethanol fermentation is a powerful approach for yeast strains to improve fermentation performance under the control of multiple genes. The transcription factor SPT3 plays a central role in improvement of ethanol and osmotic strains. Overexpression of SPT3 can increase the production of ethanol by improving osmotic tolerance and ethanol tolerance of engineered strains using glycerol. To investigate the effect of modulation of transcription factor in the fermentation properties of S. cerevisiae strains and to evaluate whether overexpression of transcription factor would result in higher ethanol yield. [1] KO Yu, SW Kim, SO Han. Biores. Technol. 2010 In press |
| 저자 | 유경옥, 한성옥 |
| 소속 | 고려대 |
| 키워드 | Glycerol; fermentation; Saccharomyces cerevisiae; Ethanol |
| 원문파일 | 초록 보기 |
