| 초록 |
Microcapsule is a promising template to utilize as a drug carrier with their uniform membrane. Membrane enables to protect encapsulates inside the core and also can release them selectively to the surroundings. However, microcapsules with size- and charge-selective permeability are still limited to introduce practical drugs, which usually have small sizes. Herein we report microfluidic approach to produce microcapsules with polarity-selective transmembrane transport using photo-curable monomers and phase change material as middle oil phase of double emulsion drops. Through photo-polymerization, membrane can form continuous oil pathway within the rigid framework. Moreover, their pathway can be regulated additionally at different temperature. As this resulting membrane possess polarity- and temperature-selective permeability, it is believed to be improve as novel drug carrier with monodisperse shape, high encapsulation efficiency, high mechanical stability and selective permeabilities. |
