화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2007년 봄 (04/12 ~ 04/13, 제주 ICC)
권호 32권 1호
발표분야 기능성 고분자
제목 Thermosensitive injectable hydrogels for controlled protein delivery
초록 Polymeric hydrogls have been widely explored for biomedical applications because of their water content and generally favorable biocompatibility. Particularly, thermosensitive hydrogels are of great interest in drug delivery, cell encapsulation, and tissue engineering. This study aims to develop a injectable, thermosensitive system based on poly(N-isopropylacrylamide) hydrogel, that can serve as a therapeutic drug delivery system promoting tissue repair and regeneration. We prepared loosely crosslinked poly(N-isopropylacrylamide-co-phosphonic acid) hydrogels and investigated their physicochemical characteristics and in vitro release kinetics of drug.
저자 김소연1, 구안나2, 이상천2, 최진섭2, 장정호2, 김경자2
소속 1충남대, 2요업(세라믹)기술원 나노소재응용본부
키워드 drug delivery; injectable hydrogels; PNIPAAm
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