| 초록 |
This talk will mostly focus on a related class of materials, DNA amphiphiles, that have synthetic hydrophobic segments covalently connected to oligonucleotides. These materials exhibit both, the self-recognition properties of DNA and the aggregation behavior of amphiphilic molecules. (1) These self-assembled objects are templating the formation of virus-like particles and at the same time allow to develop a general loading scheme for equipping virus capsids with many different payloads. (2) As a second application I demonstrate the dispersion of carbon nanotubes (CNTs) with DNA block copolymers composed of DNA and polyfluorene. While the conjugated polymer is responsible for interacting with the CNT, the DNA block mediates solubility in the aqueous phase. It was shown that gold nanoparticles can be attached by hybridization. Moreover, the solution-based self-assembly process allows deposition of CNTs on DNA modified surfaces such as filed-effect transistor (FET) in high yield. |
