화학공학소재연구정보센터
학회 한국재료학회
학술대회 2018년 가을 (11/07 ~ 11/09, 여수 디오션리조트)
권호 24권 2호
발표분야 2. 생체재료와 조직재생(Biomaterials and Tissue Regeneration)-오거나이저: 이병택 교수(순천향대)
제목 Current applications of various metal 3-D printed implant for spine and brain surgery
초록 Various material is using in the neurosurgical care. Interbody fusion is standard surgical procedure for various degenerative spinal disc disease such as well as spinal stenosis, various degree of spondylolisthesis. Many kinds of interbody cages for replace prosthesis for removed disc has been developed so far. Initial material was made from titanium block. We would like to mention about new material of interbody prosthesis for lumbar disc replacement prosthesis. Artificial disc has quite another biophysical property and let it to the irrelevancy to the subject. 3d printed titanium caldarium is using for the cranioplasty surgery
Initial starting material of lumbar interbody prosthesis was cylindrical threaded cage made of titanium. But the too narrow contact surface of cylindrical cage on the bony endplate was blamed as considerable subsidence during follow up. The cylindrical cage was rapidly replaced the rectangular-shape cage which has more large contact surface and showed more stable result. The rectangular-shape cage made from titanium was prevail and it showed also subsidence in some cases and the big difference of elastic modulus between titanium and cortical or cancellous bone was pointed out as a culprit. This gap of elastic modulus lead the change of material from titanium to PEEK (polyethyletherketon) or CFRP (carbon fiber reinforce PEEK) which has similar elasticity with bone tissue and showed more favorable results. The cage made from PEEK is most prevalent material for lumbar disc replacement nowadays. But PEEK has the inherent property of low bone-implant integration. The peek cages is just acting as a spacer but not fused as an integrator. In another words. The fusion process of PEEK was only around cage and through the cavity in the cage but not on the surface of PEEK itself. Meanwhile, 3 dimensional printing technique for various metal substance has been evolved and key patent of 3D-printing has expired. Now the stand alone cage stands in the front of another corner of development. Titanium can be printed by 3D metal printer and the elastic modulus can be adjustable by modulating configuration and amount of matrix structures inside of cage.  
The authors applied 3D printed titanium cage for 6 patient with spinal stenosis and spondylolisthesis via the unilateral transforaminal lumbar interbody fusion and percutaneous pedicle screw insertion surgery. The fusion process of every cases were successful and clinical result was also excellent. The presentation will shows the 6 months follow-up result.
The titanium matrix cages and skull caldarium is immerging material printed by metal 3D printer and look promising for elastic modulus and bone implant integration.
저자 임수빈
소속 순천향대
키워드 Neuro surgery; 3D-printed implant
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