| 학회 |
한국공업화학회 |
| 학술대회 |
2021년 봄 (05/12 ~ 05/14, 부산 벡스코(BEXCO)) |
| 권호 |
25권 1호 |
| 발표분야 |
포스터-생물공학 |
| 제목 |
Engineering fast growing cyanobacterium Synechococcus elongatus UTEX 2973 for increasing the polyhydroxybutyrate (PHB) production derived by CO2. |
| 초록 |
A novel PHB-producing cyanobacterial strain was developed by harnessing fast-growing cyanobacteria Synechococcus elongatus UTEX 2973 with introduction of heterologous phaCAB genes. Under photoautotrophic condition, the engineered strain produced 420 mg L− 1 (16.7% of dry cell weight) with the highest specific productivity of 75.2 mg L− 1 d− 1 . When compared with a native PHB producer Synechocystis PCC 6803 under nitrogen deprivation, the engineered strain exhibited 2.4-fold higher PHB productivity. The performance of the engineered strain was further demonstrated in large scale cultivation using photobioreactor and outdoor cultivation employing industrial flue gas as the sole carbon source. This study can provide a promising solution to address petroleum-based plastic waste and contribute to CO2 mitigation. |
| 저자 |
서영현1, 장원석2, 심상준1
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| 소속 |
1고려대, 2한국지역난방공사 |
| 키워드 |
Polyhydroxybutyrate; Strain engineering; Bioplastic; Carbon capture and utilization
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| E-Mail |
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