| 학회 | 한국공업화학회 |
| 학술대회 | 2015년 가을 (11/04 ~ 11/06, 제주국제컨벤션센터(ICCJEJU)) |
| 권호 | 19권 2호 |
| 발표분야 | 생물공학_포스터 |
| 제목 | Systematic Evolution of Ligands by Exponential Enrichment (SELEX) for RNA aptamer that particularly binds to ε-caprolactam |
| 초록 | ε-Caprolactam is a monomer of Nylon 6 used for fiber and plastic, and the global ε-caprolactam market is estimated to $US 10.6 billion per year. RNA aptamer is applicable for diverse fields such as therapeutic agent, research reagent, and diagnosis. Because RNA aptamer that specifically binds to ε-caprolactam has not been discovered or developed, we performed systematic evolution of ligands by exponential enrichment (SELEX) that consists of repeated series of processes in order to obtain synthetic RNA aptamer for caprolactam. We carried out several rounds of SELEX and obtained a pool of RNA aptamer and the enriched aptamer pool can be applied in various areas of biotechnology where in vitro or in vivo detection of ε-caprolactam is needed. |
| 저자 | 정규열, 장성연 |
| 소속 | 포항공과대 |
| 키워드 | RNA aptamer; SELEX; ε-caprolactam |
