| 초록 |
Caprolactam is a monomer of Nylon 6 and the global market is estimated to $US 10.6 billion per year. RNA aptamer is applicable for diverse fields such as therapeutic agent, research reagent, and diagnosis. Because RNA aptamer that specifically binds to caprolactam has not been discovered or developed, we performed systematic evolution of ligands by exponential enrichment (SELEX). We carried out several rounds of SELEX and obtained a pool of RNA aptamer. We expect that the enriched aptamer pool can be applied in various areas of biotechnology where detection of caprolactam is needed. This work was supported by Advanced Biomass R&D Center(ABC-2010-0029800) funded by the National Research Foundation of Korea and the Marine Biomaterials Research Center of the Marine Biotechnology Program funded by the Ministry of Land, Transport and Maritime Affairs, Korea. |
