| 학회 |
한국화학공학회 |
| 학술대회 |
2009년 봄 (04/23 ~ 04/24, 광주 김대중컨벤션센터) |
| 권호 |
15권 1호, p.42 |
| 발표분야 |
고분자 |
| 제목 |
pH-dependent Drug Release Behavior of Chitosan-Alginate Blend Containing Activated Carbon |
| 초록 |
Chitosan-alginate blend particles were prepared for a drug delivery carrier. In order to increase the loading capacity of dug, activated carbon was incorporated as an adsorbent of drug due to the extremely high surface area and pore volume. The composite of chitosan-alginate blend and activated carbon was studied by SEM and XRD to investigate the surface morphology and structural characteristics. The drug release from the composite was carried out at various pH conditions in order to investigate the optimized dissolution condition of chitosan-alginate matrix. It was confirmed that the efficiency of drug loading was improved by activated carbon and the drug was released mostly at basic pH condition. |
| 저자 |
진동휘, 윤주미, 이영석, 김형일
|
| 소속 |
충남대 |
| 키워드 |
Chitosan; alginate; Activated Carbon; drug delivery
|
| E-Mail |
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| 원문파일 |
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