화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2008년 가을 (11/12 ~ 11/14, ICC 제주)
권호 12권 2호
발표분야 고분자
제목 A Field-Effect Transistor Sensor of AptamerConjugated Conducting Polymer Nanotube for Electrochemical Protein Recognition
초록 A fieldeffect transistor (FET) sensor platform was manufactured to recognize particular biological objects by employing a buffer solution as a liquidion gate. Carboxylic acid-conjugated polypyrrole (CPPy) nanotubes were covalently incorporated into the microelectrode substrate, and thrombin aptamers were immobilized onto the nanotube surface as the molecular detection element. The FET sensor response was adjusted by tuning the chemical functionality of CPPy nanotubes, providing an effective way to sensitivity control. Accordingly, it is expected that CPPy nanotubes can be applied to smart signal transducers as well as molecular probes or DNA/protein carriers.
저자 오완규, 윤현석, 장정식
소속 서울대
키워드 aptamers; biosensors; nanotubes; polypyrrole; field-effect transistors
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