| 학회 | 한국화학공학회 |
| 학술대회 | 2007년 봄 (04/19 ~ 04/20, 울산 롯데호텔) |
| 권호 | 13권 1호, p.268 |
| 발표분야 | 분리기술 |
| 제목 | Competitive Isothermal Adsorption Equilibria of L-Ribose and L-Arabinose on Ion-Exchange Resin of Ca2+ Form |
| 초록 | D-ribose is naturally used a form of deoxyribose as the vehicle of genetic codes in living organisms. On the other hand, L-ribose and its derived nucleosides have a potential as anti-viral agents, such as a precursor of anti-hepatitis B virus (HBV) drug. Chemical or enzymatic process for the synthesis of L-ribose had been employed and its results had been reported by several researchers. L-arabinose had been also reported the intermediate of L-ribose synthetic processes. In this study, experiments to measure the isotherm behaviors of two L-form sugars under variable conditions were performed for the separation and the purification of L-ribose and L-arabinose using ligand-exclusion chromatography. The Dow 50WX4 (Ca2+ form) was employed as the separation resin. From the results, it was shown that the isotherm behaviors of L-ribose and L-arabinose interacted competitively. |
| 저자 | 김진일, 박영수, 이주원, 김정근, 구윤모 |
| 소속 | 인하대 |
| 키워드 | LC; ligand-exclusion chromatography; L-ribose; L-arabinose; isotherm; competitive isotherm; SMB |
| 원문파일 | 초록 보기 |
