| 학회 |
한국공업화학회 |
| 학술대회 |
2018년 봄 (05/02 ~ 05/04, 대구 엑스코(EXCO)) |
| 권호 |
22권 1호 |
| 발표분야 |
콜로이드계면화학_포스터 |
| 제목 |
Divalent Metal-mediated Formation of Polymeric Nanoparticles via End-modified Block-copolymers with Pyrene Fluorophore |
| 초록 |
A series of block-copolymers containing poly(ethylene glycol) and poly(acrylic acid) were synthesized via nitroxide-mediated radical polymerization with mPEG-modified alkoxyamine initiator. The resulting copolymers were end-functionalized with maleimide-modified pyrene, a well-known fluorescence probe. Pyrene-labeled block-copolymers were then subjected to encapsulate the biologically active metal ions, such as Mn(II), which can lead to the formation of core/shell-type polymeric nanoparticles in aqueous solution. The pyrene fluorophore further allows for the enhanced colloidal stability and a concomitant monitoring of drug-release. |
| 저자 |
신현우, 이상민
|
| 소속 |
가톨릭대 |
| 키워드 |
block-copolymer; pyrene; colloidal micelles
|
| E-Mail |
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