| 학회 | 한국화학공학회 |
| 학술대회 | 2017년 가을 (10/25 ~ 10/27, 대전컨벤션센터) |
| 권호 | 23권 2호, p.1723 |
| 발표분야 | 생물화공 |
| 제목 | Equilibrium, Kinetics and Thermodynamic Adsorption of Paclitaxel from Taxus chinensis onto Sylopute |
| 초록 | Abstract Batch experiment studies were carried out on the adsorption of paclitaxel using sylopute. The experimental data were fitted to the Langmuir, Freundlich, Temkin and Dubinin-Radushkevich isotherm models. Comparison of results revealed that the Freundlich isotherm model could account for the adsorption isotherm data with the highest accuracy among the four isotherm models considered. From the analysis of adsorption isotherms, it was found that adsorption capacity increased with increasing temperature and the adsorption of paclitaxel onto sylopute was favorable. The obtained kinetics data for paclitaxel adsorption onto sylopute agreed well with the pseudo-second-order model. Thermodynamic parameters, such as standard enthalpy (△H°), standard entropy (△S°) and standard Gibbs free energy (△G°) change, were investigated. The results indicated that the process of 10-deacetylpaclitaxel adsorption onto sylopute was endothermic and irreversible. Acknowledgment This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (Grant Number: 2015016271). |
| 저자 | 김예솔, 김진현 |
| 소속 | 공주대 |
| 키워드 | 생물화공 |
| 원문파일 | 초록 보기 |
