화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2011년 가을 (10/06 ~ 10/07, 김대중 컨벤션센터)
권호 36권 2호
발표분야 의료용 고분자 부문위원회
제목 Nanoparticles based on antibacterial agents conjugated Chtisan for Drug Delivery System
초록 Carboxymethylation chitosan derivatives are widely used for biomedical applications because of their nontoxic and biodegradable properties. Chitosan-antibacteral agents was prepared by chemical reaction with Chitosan and antibacteral agents for application possibility of drug delivery system. The structual characterisitcs of Chitosan-antibacteral agentswas investigated by FT-IR, 1H NMR. Particle size and zeta potential of the Chitosan-antibacteral agents was measureed using dynamic light scattering technique. For a molecular weight measurement used gel permeation chromatograph(GPC). The release behaviors of Chitosan-antibacteral agents from this proposed delivery system in phosphate-buffered saline (PBS) solution at 37 °C were studied by fluorescence spectroscopy.
저자 남정표, 김영민, 이경재, 박준규, 김원석, 최창용, 장미경, 나재운
소속 순천대
키워드 carboxymethylation chitosan; antibacteral agents; DDS
E-Mail