| 초록 |
Titanium dioxide(TiO2) is well known as photosensitizer(PS) but this semiconductor has the large band gap of 3.0 or 3.2 eV, allowing for the absorption of only UV light. In this work, we synthesized highly uniform gold nanoparticle(AuNP) and TiO2 hybrid structures with tailored Au architecture. It has been reported that this gold nanoparticles(AuNPs) with tailored shape can have LSPR band in the NIR range and they are expected to possess stronger local field and narrower spectral LSPR band. When the gold core absorbs NIR laser of 808 nm wavelength, surface plasmons are excited and the field is sufficiently energetic to be transferred to the conduction band of TiO2 shell over the Schottky barrier. These hot electrons react with oxygen molecules in the medium to generate reactive oxygen species(ROS). Thus, a unique type of multifunctional hybrid nanomaterials with both photo-dynamic and photo-thermal therapeutic effects under NIR light can be established. |
