초록 |
Label-free, sensitive and selective detection methods with high spatial resolution are critically required for future applications in chemical sensor, biological sensor, and nanospectroscopic imaging. Fluorophore or quantum dot-based detection are facing their limit due to photobleaching and blinking, and plasmonic-based sensing methods such as Surface Plasmon Resonance (SPR), Localized Surface Plasmon Resonance (LSPR), and Surface Enhanced Raman Spectroscopy (SERS) are limited in spatial resolution, molecular finger print information, or uniformity of detection. However, these limits can be overcome by using the recently introduced plasmon based detection method, Plasmon Resonance Energy Transfer (PRET). |