| 초록 |
The intermediates formed during phenanthrene biodegradation significantly alters toxicity of soil environment and overall degradation rates. The main intermediates are 1-hydroxy-2-naphthoic acid, salicylic acid, and cis-3,4-dihydroxy-3,4-dihydrophenanthrene. However, many other intermediates have not been detected in the extracellular media. This may be related with the release of intermediates from the cell membrane. In this study we developed models based on Fick's Law to estimate release pattern of intermediates during phenanthrene degradation. We analyzed 14 enzymatic steps and intermediates occurred in complete phenanthrene degradation. The chemical properties of some intermediates were estimated using group theory. From the model, it was obtained that 3,4-dihydroxyphenanthrene, 1-hydroxy-2-naphthaldehyde, and catechol had higher permeability coefficients than other intermediates. The results from model estimation provide good explanation why only a few intermediates are found during phenanthrene degradation in natural environments or laboratory experiments. |
