| 초록 |
Curcumin(natural antimicrobial agent) became used in Indian traditional medicine and it is one of the three curcuminoids present in turmeric. Polyrhodanine(PRd, antimicrobial polymer) has attracted considerable attention in various application fields such as anticorrosion, antibacterial, and antihistaminic agents. In this study, we synthesized curcumin/PRd nanoparticle with microbial disinfection property to release control by the encapsulation of natural antimicrobial agent and antimicrobial polymer. The size and morphology of curcumin/PRd nanoparticle were analyzed by DLS and FE-SEM(average 200nm). The thermal stability of curcumin/PRd nanoparticle was confirmed by TGA. The release bahavior and synthetic mechanism of curcumin/PRd nanoparticle was demonstrated by UV-vis, HPLC(high performance liquid chromatography), FT-IR and XRD(X-ray diffraction). |
