| 학회 |
한국고분자학회 |
| 학술대회 |
2009년 가을 (10/08 ~ 10/09, 광주과학기술원 오룡관) |
| 권호 |
34권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Release rate control of liposome using diacrylated-pluronic |
| 초록 |
Liposome is useful for delivery of hydrophilic drugs that cannot be loaded efficiently into other drug delivery systems. However, control of release rate from liposomal system is hard to achieve. In this study, we applied diacrylated-pluronic to control the permeability of lipid bilayer. Diacrylated-pluronic was coated on the lipid bilayer of liposome, and photo-crosslinked. The release rate of dimethylmethylene blue, a water soluble dye, from pluronic-coated liposome was controlled by the concentration of diacrylated-pluronic during coating process. Acknowledgement : This research was supported by a grant (code #: R01-2007-000-20493-0) from KOSEF |
| 저자 |
김종철1, 설동근2, 황선욱2, 이상헌2, 김영하1, 태기융1
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| 소속 |
1광주과학기술원 신소재공학과, 2고려대 |
| 키워드 |
controlled release; liposome
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| E-Mail |
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