| 초록 |
We synthesized new series of tri-component copolymers by ring opening copolymerization of cyclic lactons, i.s. glycolide, L-Lactide and ε-caprolactone, in the presence of stannous octoate as a catalyst. Then we studied physical and chemical characteristics of PGLCL copolymer. Various technique, including 1H-NMR, GPC, DSC, tensile strength were used for examining structural characteristics, thermal behaviors, mechanical properties and elasticity of PGLCL copolymers. Furthermore, we performed in vitro degradation tests for 12 weeks and observed changes of molecular weight, gross weight and compositions. Consequently, the mechanical properties and degradability of PGLCL terpolymers could be controlled by changing the monomer content thus increasing the range of applications to mechano-active tissue engineering depending on demands in mechanical properties. |
