| 초록 |
Poly(p-dioxanone) (PPDO) is a crystalline, biodegradable and biocompatible aliphatic polyester with high flexibility and good tensile strength. The compatibility, degradation rate and mechanical properties of PPDO are of interest when considering the design of tissue engineering scaffolds. In this research, PPDO was synthesized by ring-opening polymerization of the monomer, p-dioxanone (PDO). The PPDO nanofibers were fabricated by electrospinning of the PPDO in DMSO at high temperatures (60 ~ 90 oC), because PPDO was partially insoluble at room temperature. Nanocomposites of PPDO containing laponite (LAP) and vermiculite (VMT) as nanofibers were also electrospun in DMSO at high temperatures. When the contents of the PPDO were increased, uniform PPDO nanofibers were obtained. The morphology and structure of the electrospun nanofibers were investigated by FE-SEM, FE-TEM, DSC, and WAXD. DSC and WAXD were used to analyze the crystallinity of the electrospun ultrafine fibers. |
